Search
Research
In-utero exposures and the evolving epidemiology of paediatric allergyThis paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune...
Research
In utero and postnatal vitamin D exposure and allergy riskThis review article examines the evidence of the impact of in utero and postnatal vitamin D exposure on allergy risk in childhood
Research
Nutritional Influences on Epigenetic Programming. Asthma, Allergy, and ObesityReliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also...
Research
25-hydroxyvitamin D3 status is associated with developing adaptive and innate immune responses in the first 6 months of lifeVitamin D status in early life has been linked to the risk of allergic disease in multiple observational studies.
Research
Fish oil supplementation in early infancy modulates developing infant immune responsesMaternal fish oil supplementation during pregnancy has been associated with altered infant immune responses and a reduced risk of infant sensitization and...
Research
Ontogeny of toll-like and NOD-like receptor-mediated innate immune responses in Papua New Guinean infantsStudies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in...
Research
Comparison of neonatal T regulatory cell function in Papua New Guinean and Australian newbornsWe compared neonatal T reg from children born in western conditions (Australia) with those of neonates born in high microbial conditions (Papua New Guinea)...
Research
A novel role for interleukin-1 receptor signaling in the developmental regulation of immune responses to endotoxinSuggests that IL-1R1 expression provides an additional level of Myd88-dependent signaling during this period of heighted susceptibility to infection.
Research
T-cell activation genes differentially expressed at birth in CD4+ T-cells from children who develop IgE food allergyTo show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy.
Research
The relationship between maternal folate status in pregnancy, cord blood folate levels, and allergic outcomes in early childhoodThis study examined whether maternal and/or fetal folate status in pregnancy is associated with infant allergic outcomes.