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Research

Evolution of pulmonary inflammation and nutritional status in infants and young children with cystic fibrosis

Improved nutrition is the major proven benefit of newborn screening programmes for cystic fibrosis (CF) and is associated with better clinical outcomes.

Research

The placenta and neurologic and psychiatric outcomes in the child: Study design matters

Much information exists about functions of the human placenta and about potential mechanisms by which the placenta may influence human health or disease...

Research

Extent of metabolic risk in adolescent girls with features of polycystic ovary syndrome

The objective of this study was to determine prevalence of metabolic syndrome in adolescents with polycystic ovary syndrome (PCOS)

Research

Group A Streptococcal Diseases and Their Global Burden

We review GAS transmission characteristics and prevention strategies, historical and geographical trends and report on the estimated global burden disease...

Research

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010

Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a...

Research

The future of acute rheumatic fever and rheumatic heart disease in Australia

Globally, ARF and RHD cause more than a quarter of a million deaths and substantial disability each year.

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Characterization of regulatory dendritic cells differentiated from the bone marrow of UV-irradiated mice

In summary, UV-BMDCs do not express the classical phenotypic or gene expression properties of DCs reported by others as 'regulatory' or 'tolerogenic'.

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The Global Lung Initiative 2012 reference values reflect contemporary Australasian spirometry

We aimed to ascertain the fit of the European Respiratory Society Global Lung Initiative 2012 reference ranges to contemporary Australasian spirometric data.

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Acute diesel exhaust particle exposure increases viral titre and inflammation associated with existing influenza

Exposure to diesel exhaust particles (DEP) is thought to exacerbate many pre-existing respiratory diseases.

Research

Safety and immunogenicity of a meningococcal B bivalent rLP2086 vaccine in healthy toddlers Aged 18-36 months

A bivalent, recombinant, factor H-binding protein (rLP2086) vaccine was developed to protect against invasive Neisseria meningitidis serogroup B (MnB) in...