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Value profile for Malaria vaccines and monoclonal antibodies1Malaria remains a leading cause of morbidity and mortality and is responsible for over 0.5 million annual deaths globally. During the first two decades of this century, scale-up of a range of tools was associated with significant reductions in malaria mortality in the primary risk group, young African children.
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The seroprevalence of SARS-CoV-2-specific antibodies in Australian children: A crosssectional studyFollowing reduction of public health and social measures concurrent with SARS-CoV-2 Omicron emergence in late 2021 in Australia, COVID-19 case notification rates rose rapidly. As rates of direct viral testing and reporting dropped, true infection rates were most likely to be underestimated.
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Rationale for use for monoclonal antibody and anti-cytokine therapy for multisystem inflammatory syndrome in children: A systematic reviewObjective: To review systematically the rationale for choice and use of monoclonal antibody and anti-cytokine therapy in multisystem inflammatory syndrome in children.
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Treatment for Childhood and Adolescent Dissociation: A Systematic ReviewDissociative symptoms are linked to experiences of trauma, often originating in childhood and adolescence. Dissociative disorders are associated with a high burden of illness and a poor quality of life. Despite evidence suggesting that early intervention can improve outcomes, little research exists on the treatment of dissociative disorders in childhood and adolescence.
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Towards Harmonized Adolescent Health Measurement: Assessing Alignment Between Current Recommendations and the Global Action for Measurement of Adolescent Health–Recommended IndicatorsThis study identified alignment of indicators across different initiatives and data collection instruments as a foundation for future harmonization of adolescent health measurement.
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Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathwaysnfants with frequent viral and bacterial respiratory infections exhibit compromised immunity to routine immunizations. They are also more likely to develop chronic respiratory diseases in later childhood. This study investigated the feasibility of epigenetic profiling to reveal endotype-specific molecular pathways with potential for early identification and immuno-modulation.
News & Events
Groundbreaking TB researcher named AAMRI Rising StarDr Kefyalew Alene, who heads the Geospatial and Tuberculosis team at The Kids and is a senior research fellow within the Curtin School of Population Health, has used cutting edge technology to transform the way TB transmission is predicted, understood and managed globally.
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Research breakthrough gives hope to children with rare and undiagnosed diseasesA complex five-year experiment which cracked the code of a genetic mystery has paved the way for faster and more accurate diagnoses of the most rare and unknown diseases affecting children.
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Pitch perfect projects powered by philanthropyEarlier this week ten emerging researchers took to the stage to pitch their projects to a room full of excited and engaged philanthropists who share our vision of happy, healthy kids.
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Flying the flag for WA research thanks to Business Events Aspire AwardsDr Matthew ‘Tepi’ Mclaughlin is the 2022 The Kids Research Institute Australia Aspire Award winner - coordinated by Western Australia’s peak body for business events, Business Events Perth.