Search
Research
Long-term derangement of antigen presenting cell populations in the respiratory tract following Influenza A infectionThis project investigates how different populations of cells within the respiratory tract immune system are altered during a viral infection.
News & Events
WA researchers lead global centre to eliminate childhood asthmaAn ambitious project that could stop children developing asthma is the centrepiece of a new world-class respiratory research centre launched in Perth.
News & Events
ORIGINS Project shines light on Early Childhood DevelopmentA collaboration between The Kids Research Institute Australia and Joondalup Health Campus is poised to be a game-changer for early childhood development.
News & Events
New lease on life for DartanyonTwo years on, Michelle and Dartanyon’s health and quality of life have significantly improved. We caught up with Michelle to hear about their journey since we first met them.
Research
Bronchodilator responsiveness in children with asthma is not influenced by spacer device selectionSpacer device was not associated with clinically important differences in lung function following bronchodilator inhalation in children with asthma
Research
IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced ReprogrammingHigh risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high versus low susceptibility to experimental asthma, induced by virus/allergen coexposure, to elucidate the mechanism(s)-of-action of the high-risk asthma immunophenotype.
Research
Epigenome-wide meta-analysis of DNA methylation and childhood asthmaNovel loci differentially methylated in newborns represent potential biomarkers of risk of asthma by school age
Research
After asthma: Redefining airways diseasesIdentify entrenched areas of asthma management and treatment in which progress has stalled and to challenge current principles
Research
Children with East Asian-Born Parents Have an Increased Risk of Allergy but May Not Have More Asthma in Early ChildhoodChildren of East Asian ancestry born in Australia have a higher burden of most allergic diseases in the first 6 years of life, whereas asthma may follow a different pattern
Research
Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute WheezingAsthma exacerbations in children can be divided into IRF7hi versus IRF7lo phenotypes with associated differences in clinical phenotypes