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Study protocol of a multicentre, randomised, controlled trial evaluating the effectiveness of probiotic and peanut oral immunotherapyPeanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment. There is a pressing need for definitive treatments that improve the quality of life and prevent fatalities. Allergen oral immunotherapy (OIT) is a promising approach, which is effective at inducing desensitisation; however, OIT has a limited ability to induce sustained unresponsiveness (SU).
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Association Between Family Characteristics and the Effect of Timing of Regular Egg Introduction in Infant Egg AllergyA recent systematic review of 5 randomized clinical trials, found that early egg introduction was associated with reduced egg allergy.
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Childhood Overweight and Obesity: Maternal and Family FactorsThe need to target prevention and intervention efforts for childhood overweight and obesity towards families with overweight parents
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The establishment of DOHaD working groups in Australia and New ZealandThis report introduces the DOHaD ANZ Working Groups and summarizes their plans and activities
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The psychosocial burden of childhood overweight and obesity: evidence for persisting difficulties in boys and girlsOverweight and obese children reported greater psychosocial distress than healthy weight children, and these differences were more pronounced for girls than boys.
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Can polymorphisms in the fatty acid desaturase (FADS) gene cluster alter the effects of fish oil supplementation on plasma and erythrocyte fatty acid profiles? An exploratory studyOverall results of this preliminary study suggest that supplementation with fish oil may only significantly increase DHA in minor allele carriers of FADS1 SNPs. Further research is required to confirm this novel finding.
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Epigenetic modifications: Mechanisms of disease and biomarkers of food allergyThe rise in IgE-mediated food allergy in recent times is the likely result of gene-environment interactions mediated via epigenetic pathways.
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Influence of maternal obesity on the long-term health of offspringIncreasing evidence implicates maternal obesity as a major determinant of offspring health during childhood and later adult life
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Comparison of neonatal T regulatory cell function in Papua New Guinean and Australian newbornsWe compared neonatal T reg from children born in western conditions (Australia) with those of neonates born in high microbial conditions (Papua New Guinea)...
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Fish oil supplementation in early infancy modulates developing infant immune responsesMaternal fish oil supplementation during pregnancy has been associated with altered infant immune responses and a reduced risk of infant sensitization and...